Age and Transmissible Spongiform Encephalopathies
نویسندگان
چکیده
infections. The spread of CTXM–positive bacteria considerably changes the way we think about treating community-acquired infections and limits the oral antibiotics that may be administered. This finding has major implications for treating children, who should not be given fluoroquinolones and tetracyclines. The observation that different blaCTX-M alleles, located on plasmids of different sizes, were involved in clinical infections caused by distinct E. coli clones implies that CTX-M enzymes may become widespread in the community. A possible association of blaCTX-M genes with insertion sequences like ISEcp1B might have contributed to the enhanced expression and mobilization of blaCTX-M genes among E. coli isolates (7). The apparent dissemination of CTX-M producers could represent a substantial barrier in the treatment of community-acquired infections. Additionally, severely ill patients treated in the outpatient setting may transmit such resistant organisms to hospitalized patients.
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2004